Renal Medulla and Renoprival Hypertension
نویسنده
چکیده
• Nephreetomized dogs given sodium parenterally and protein by diet develop acute hypertensive cardiovascular disease.' Protection, against acute renoprival hypertension of this type has been demonstrated for (a) intact renal tissue as exemplified by ureterocaval anastomosis, (b) autoexplanation of whole kidney or renal medulla, and (c) a crude extract of renal medulla. Both medullorenal extract and renal tissue without an excretory outlet protect also against the acceleration of renoprival hypertension due to large sodium loads in the absence of food intake.-
منابع مشابه
Renomedullary Vasodepressor Substance, Medullin: Isolation, Chemical Characterization and Physiological Properties.
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متن کاملDiscovery of the renomedullary system of blood pressure control and its hormones.
I worked with Arthur Grollman for 3Vi years (and 12 scientific publications) beginning in 1947. Arthur was Chairman of the Department of Experimental Medicine, and I became Chairman of the Department of Pathology at Southwestern Medical School in Dallas. Grollman inoculated me with his concept of a "nonexcretory antihypertensive function of the kidney", "incretory" he termed it. For some time, ...
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